SCLY 蛋白, Human (His)

SCLY protein plays an important role in selenium metabolism by catalyzing the decomposition of L-selenocysteine to produce L-alanine and elemental selenium. This enzymatic process is critical for regulating intracellular selenium utilization and recycling. SCLY Protein, Human (His) is the recombinant human-derived SCLY protein, expressed by E. coli , with N-6*His labeled tag.

硒代半胱氨酸裂解酶（SCLY）是一种在 L-硒代半胱氨酸的分解中起关键作用的酶。具体来说，SCLY 催化将 L-硒代半胱氨酸分解为 L-丙氨酸和元素硒的反应。这种酶活性在硒代谢中具有重要意义，因为它有助于从硒蛋白中释放硒及其随后在各种细胞过程中的利用。硒代半胱氨酸是一种独特的氨基酸，可将硒融入蛋白质中，其被 SCLY 分解对于硒的回收和维持细胞硒稳态至关重要。参考文献强调了 SCLY 在硒代半胱氨酸代谢过程中的特殊作用，阐明了它在硒生物学和细胞硒水平调节中的重要性。

Human

E. coli

N-6*His

Q96I15-1 (M1-A445)

51540  [NCBI]

MEAAVAPGRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCNFSIRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQLEDQA

50-55 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.