1. 重组蛋白
  2. Enzymes & Regulators
  3. Hydrolases (EC 3)
  4. SENP8 蛋白, Human (His)

SENP8 蛋白是 NEDD8 通路中的关键蛋白酶,在催化全长 NEDD8 加工成成熟形式和促进 NEDD8 与特定靶蛋白(包括 cullin 和 p53)解偶联方面发挥着双重作用。SENP8 的双重功能强调了其在调节 NEDD8 修饰、影响各种细胞途径和功能中的关键作用。SENP8 蛋白, Human (His) 是重组的 SENP8 蛋白,由 E. coli 表达,带有 N-6*His 标签。SENP8 蛋白, Human (His) 全长 212 个氨基酸,分子量约为 ~22.0 kDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

SENP8 protein, a pivotal protease in the NEDD8 pathway, plays a dual role in catalyzing the processing of full-length NEDD8 into its mature form and facilitating the deconjugation of NEDD8 from specific target proteins, including cullins and p53. SENP8's dual functionality underscores its crucial role in regulating NEDD8 modification, impacting various cellular pathways and functions. SENP8 Protein, Human (His) is the recombinant human-derived SENP8 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SENP8 Protein, Human (His) is 212 a.a., with molecular weight of ~22.0 kDa.

研究背景

SENP8 蛋白是 NEDD8 通路中的关键蛋白酶,发挥双重作用:催化全长 NEDD8 加工成成熟形式,并促进 NEDD8 与特定靶蛋白(包括 cullin 和 p53)解偶联。这种双重功能强调了 SENP8 在调节 NEDD8 修饰中的关键参与,这一过程对各种细胞途径和功能具有深远的影响。

种属

Human

表达系统

E. coli

标签

N-6*His

蛋白编号

Q96LD8 (M1-K212)

基因 ID
蛋白结构
N-term
6*His
SENP8 (M1-K212)
Accession # Q96LD8
C-term
同用名
Sentrin-Specific Protease 8; Deneddylase-1; NEDD8-Specific Protease 1; Protease Cysteine 2; Sentrin/SUMO-Specific Protease SENP8; SENP8; DEN1; NEDP1; PRSC2
氨基酸序列

MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK

分子量

Approximately 22.0 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

SENP8 Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
SENP8 Protein, Human (His)
目录号:
HY-P71290
需求量: