SENP8 - SUMO peptidase family member, NEDD8 specific Gene

中文名称：SUMO 肽酶家族成员，NEDD8 特异性

种属: Homo sapiens

同用名: DEN1; NEDP1; PRSC2

基因 ID: 123228 | 基因类型: protein coding

关于 SENP8

Cytogenetic location: 15q23 Genomic coordinates (GRCh38): 15:72,114,258-72,143,692 (from NCBI)

This gene has 5 transcripts (splice variants), 202 orthologues and 2 paralogues. Broad expression in testis (RPKM 2.2), thyroid (RPKM 1.6) and 23 other tissues.

功能概要

该基因编码的半胱氨酸蛋白酶是哨兵特异性蛋白酶家族的一员。编码的蛋白质参与泛素样蛋白质的加工和解偶联，称为神经前体细胞表达发育下调 8。交替剪接导致多个转录变体。[RefSeq 提供，2009 年 10 月]

This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

SENP8 基因产物(5)

mRNA	Protein	Name
NM_001166340.2	NP_001159812.1	sentrin-specific protease 8
NM_001172109.1	NP_001165580.1	sentrin-specific protease 8
NM_001172110.1	NP_001165581.1	sentrin-specific protease 8
NM_001172111.2	NP_001165582.1	sentrin-specific protease 8
NM_145204.4	NP_660205.3	sentrin-specific protease 8

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	32296183	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SENP8 蛋白结构

Peptidase_C48

0
100
200
212 a.a.

蛋白主名

其他名称

sentrin-specific protease 8

NEDD8 specific-protease cysteine 2

重组 SENP8 蛋白

目录号	产品名	蛋白编号	纯度
HY-P71290	SENP8 Protein, Human (His)	Q96LD8 (M1-K212)	≥95%

关联疾病

疾病名称

别名

St. Louis Encephalitis

Saint Louis Encephalitis	Neuroinvasive St. Louis Encephalitis Virus Infection
Encephalitis, St. Louis	Neuroinvasive Saint Louis Encephalitis Virus Infection
St. Louis Encephalitis Virus Infection	St. Louis Encephalitis Virus Neuroinvasive Disease
St. Louis Viral Disease	Type C Lethargic Encephalitis
Encephalitis Type C

Kunjin Encephalitis

Kyasanur Forest Disease

Kfd	Monkey Fever
Kfd Virus	Kyasanur Hemorrhagic Fever
Monkey Disease	Monkey Diseases
Kfd - [ Kyasanur Forest Disease]	Monkey Sickness

Asymptomatic Dengue

Dengue Hemorrhagic Fever

Severe Dengue	Dengue Haemorrhagic Fever
Dhf	Severe Dengue Haemorrhagic Fever
Severe Dengue Fever	Dengue Shock Syndrome

Panophthalmitis

Dengue Disease

Dengue Fever	Dengue
Df	Dengue Shock Syndrome
Dengue Virus Infection	Breakbone Fever
Classic Dengue	Classical Dengue
Dengue Hemorrhagic Fever	Hemorrhagic Dengue
Philippine Hemorrhagic Fever	Singapore Hemorrhagic Fever
Thai Hemorrhagic Fever	Severe Dengue
Dengue Fever Without Warning Signs	Dengue Haemorrhagic Fever Grade 1
Dengue Haemorrhagic Fever Without Warning Signs	Bangkok Haemorrhagic Fever
Singapore Haemorrhagic Fever	Thailand Haemorrhagic Fever
Southeast Asia Haemorrhagic Fever	Dhf -[Dengue Haemorrhagic Fever]
Dengue Fever With Warning Signs	Dengue Haemorrhagic Fever With Warning Signs
Dengue Haemorrhagic Fever Grade 2	Philippine Haemorrhagic Fever

Dengue Shock Syndrome

Dss

Murray Valley Encephalitis

Australian Encephalitis	Australian X Disease
Encephalitis Australia	Murray River Encephalitis
Australian Arboencephalitis	Australian X Disorder
Mve - [Murray Valley Encephalitis]

Acalculous Cholecystitis

Acute Cholecystitis Without Calculus	Acute Acalculous Cholecystitis
Cholecystitis Without Calculus

Acute Hemorrhagic Encephalitis

Japanese Encephalitis

Japanese B Encephalitis	Je
Encephalitis Japanese	Encephalitis, Japanese
Russian Autumnal Encephalitis	Je - [Japanese Encephalitis]
Japanese Encephalitis Virus Disease	Jbe - [Japanese B Encephalitis}
B Type Encephalitis

Purulent Endophthalmitis

Periocular Infection	Acute Endophthalmitis
Endophthalmia	Eye Infestation Nos
Intraocular Infection	Eye Infection Nos

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS12677	SENP8 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	SENP8	MGD	MGI:1918849
Macaca mulatta	SENP8	VGNC	VGNC:77290
Felis catus	SENP8	VGNC	VGNC:65006
Rattus norvegicus	SENP8	RGD	RGD:1309955
Canis familiaris	SENP8	VGNC	VGNC:46008
Others	SENP8	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

SENP8 - SUMO peptidase family member, NEDD8 specific Gene

关于 SENP8

功能概要

SENP8 基因产物(5)

SENP8 蛋白结构

重组 SENP8 蛋白

关联疾病

直系同源

热门区域

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SENP8 - SUMO peptidase family member, NEDD8 specific Gene

关于 SENP8

功能概要

SENP8 基因产物(5)

SENP8 蛋白结构

重组 SENP8 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z