Somatostatin R1/SSR1 蛋白, Human (HEK293, Fc)

The somatostatin R1 (SSR1) protein contains TRAP-α, TRAP-β, TRAP-δ, and TRAP-gamma, forming a heterotetramer. They play a role in binding calcium to the ER membrane and regulating the retention of ER-resident proteins. Somatostatin R1/SSR1 Protein, Human (HEK293, Fc) is the recombinant human-derived Somatostatin R1/SSR1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Somatostatin R1/SSR1 Protein, Human (HEK293, Fc) is 189 a.a., with molecular weight of ~55-75 KDa.

生长抑素 R1 (SSR1) 是一种通过与 TRAP 蛋白结合参与内质网 (ER) 膜功能调节的蛋白质。这些 TRAP 蛋白在专门将钙结合到 ER 膜上的复合物中发挥作用，从而调节驻留 ER 蛋白的保留。SSR1可能在易位过程完成后的易位装置的回收中发挥作用。或者，它可以充当膜结合伴侣，促进易位蛋白质的折叠。TRAP 蛋白的异四聚体由 TRAP-α、TRAP-β、TRAP-δ 和 TRAP-gamma 组成，与棕榈酰化钙联蛋白 (CALX) 相互作用，这种相互作用对于糖基化蛋白的有效折叠至关重要。

Human

HEK293

C-hFc

P43307-1/NP_003135.2 (V19-T207)

6745  [NCBI]

VLFRGGPRGLLAVAQDLTEDEETVEDSIIEDEDDEAEVEEDEPTDLVEDKEEEDVSGEPEASPSADTTILFVKGEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYKDLNGNVFQDAVFNQTVTVIEREDGLDGET

Approximately 55-75 kDa.

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.