ST3GAL3 蛋白, Human (His-SUMO)

ST3GAL3 protein plays a central role in cellular processes by catalyzing the formation of NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-α-2,3-Gal-beta-1,3-GalNAc- sequences are present in the terminal carbohydrate groups of glycoproteins and glycolipids. ST3GAL3 Protein, Human (His-SUMO) is the recombinant human-derived ST3GAL3 protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of ST3GAL3 Protein, Human (His-SUMO) is 347 a.a., with molecular weight of ~54.9 kDa.

ST3GAL3 或唾液酸转移酶 3 是一种催化糖蛋白和糖脂上末端碳水化合物序列形成的酶。具体来说，它负责将唾液酸添加到 Gal-beta-1,3-GlcNAc、Gal-beta-1,3-GlcNAc 和 Gal-beta-1,3-GalNAc 结构中，从而形成 NeuAc- α-2,3-Gal-β-1,4-GlcNAc、NeuAc-α-2,3-Gal-β-1,3-GlcNAc 和 NeuAc-α-2,3-Gal-β-1,3 -GalNAc序列。这些唾液酸化事件在调节糖蛋白和糖脂的结构和功能方面发挥着至关重要的作用，影响各种细胞过程。ST3GAL3 对不同底物表现出不同程度的活性，其中对 Gal-beta-1,3-GlcNAc 的活性最高，对 Gal-beta-1,3-GalNAc 的活性最低。它必须简洁地概述 ST3GAL3 在催化唾液酸添加到特定碳水化合物结构中的作用，强调其对生物分子中末端聚糖序列多样性的贡献。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

N-His;N-SUMO

Q11203 (29K-375I)

6487  [NCBI]

KLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI

Approximately 54.9 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized after extensive dialysis against solution in 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.