STC1/Stanniocalcin-1 蛋白, Human (HEK293, His)

STC1/Stanniocalcin-1 Proteinas, a homodimer, crucially stimulates renal phosphate reabsorption, safeguarding against hypercalcemia. Disulfide linkages contribute to its structural integrity. Its role in renal processes underscores significance in regulating phosphate levels, emphasizing a key role in maintaining mineral homeostasis. STC1/Stanniocalcin-1 Protein, Human (HEK293, His) is the recombinant human-derived STC1/Stanniocalcin-1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of STC1/Stanniocalcin-1 Protein, Human (HEK293, His) is 230 a.a., with molecular weight of 33-36 kDa.

STC1，也称为 Stanniocalcin-1 蛋白，在刺激肾脏磷酸盐重吸收方面发挥着至关重要的作用，从而为预防高钙血症提供了潜在的保障。该蛋白质作为同二聚体发挥作用，二硫键有助于其结构完整性和功能活性。它参与肾脏过程凸显了其在磷酸盐水平复杂调节中的重要性，表明其在维持矿物质稳态中的关键作用。

Measured in a cell proliferation assay using MCF-7 cells. The ED₅₀ for this effect is 1.019 ng/mL, corresponding to a specific activity is 9.81×10⁵ U/mg.

• 
  Measured in a cell proliferation assay using MCF-7 cells. The ED₅₀ for this effect is 1.019 ng/mL, corresponding to a specific activity is 9.81×10⁵ U/mg.

Human

HEK293

C-6*His

P52823 (T18-A247)

6781  [NCBI]

THEAEQNDSVSPRKSRVAAQNSAEVVRCLNSALQVGCGAFACLENSTCDTDGMYDICKSFLYSAAKFDTQGKAFVKESLKCIANGVTSKVFLAIRRCSTFQRMIAEVQEECYSKLNVCSIAKRNPEAITEVVQLPNHFSNRYYNRLVRSLLECDEDTVSTIRDSLMEKIGPNMASLFHILQTDHCAQTHPRADFNRRRTNEPQKLKVLLRNLRGEEDSPSHIKRTSHESA

33-36 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.