1. 重组蛋白
  2. CAR-T related Proteins CD Antigens
  3. CD138/Syndecan-1 B Cell CD Proteins Stem Cell CD Proteins Epithelial cell CD Proteins Endothelial cell CD Proteins
  4. CD138/Syndecan-1 CD138/Syndecan-1
  5. Syndecan-1/CD138 蛋白, Cynomolgus (HEK293, Fc)

Syndecan-1/CD138 蛋白, Cynomolgus (HEK293, Fc)

目录号: HY-P77219
产品使用指南

Syndecan-1/CD138 蛋白是一种细胞表面蛋白聚糖,通过硫酸乙酰肝素和硫酸软骨素将细胞骨架与间质基质连接起来。它通过 SDCBP 和 PDCD6IP 调节外泌体生物合成。Syndecan-1/CD138 蛋白通过牙细胞中的 MSX1 途径诱导其自身表达,并与 CDCP1 和 TIAM1 相互作用。它还与 MDK 相互作用,参与多种细胞过程。Syndecan-1/CD138 蛋白, Cynomolgus (HEK293, Fc) 是重组的 Syndecan-1/CD138 蛋白,由 HEK293 表达,带有 C-hFc 标签。Syndecan-1/CD138 蛋白, Cynomolgus (HEK293, Fc) 全长 229 个氨基酸,分子量约为 ~50.37 KDa。

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描述

Syndecan-1/CD138 Protein, a cell surface proteoglycan, connects the cytoskeleton to the interstitial matrix with heparan sulfate and chondroitin sulfate. It regulates exosome biogenesis with SDCBP and PDCD6IP. Syndecan-1/CD138 Protein induces its own expression through an MSX1 pathway in dental cells and interacts with CDCP1 and TIAM1. It also interacts with MDK, participating in diverse cellular processes. Syndecan-1/CD138 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived Syndecan-1/CD138 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Syndecan-1/CD138 Protein, Cynomolgus (HEK293, Fc) is 229 a.a., with molecular weight of ~50.37 KDa.

研究背景

Syndecan-1/CD138 蛋白是一种细胞表面蛋白聚糖,其特征是同时存在硫酸乙酰肝素和硫酸软骨素,在细胞骨架和间质基质之间建立联系。它与 SDCBP 和 PDCD6IP 合作,在调节外泌体生物发生中发挥作用。此外,Syndecan-1/CD138 能够通过 MSX1 介导的途径在牙齿间充质细胞和邻近的牙齿上皮细胞中诱导自身表达。它与 CDCP1 相互作用,并通过其 C 端和 TIAM1 的 PDZ 域与 TIAM1 关联。此外,Syndecan-1/CD138 与 Midkine (MDK) 相互作用[1][2][3]

种属

Cynomolgus

表达系统

HEK293

标签

C-hFc

蛋白编号

XP_005576533 (Q23-E251)

基因 ID
蛋白结构
N-term
CD138 (Q23-E251)
Accession # XP_005576533
hFc
C-term
同用名
Syndecan-1; SYND1; CD138; SDC1; SDC
分子量

Approximately 50.37 kDa.

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Syndecan-1/CD138 Protein, Cynomolgus (HEK293, Fc)
目录号:
HY-P77219
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