TALDO1 蛋白, Human (HEK293, His)

The TALDO1 protein plays a key role in cellular metabolism by catalyzing the rate-limiting step in the non-oxidative phase of the pentose phosphate pathway. Multiple studies have shown that it promotes the reversible conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate into erythrose 4-phosphate and β-D-fructose 6-phosphate. TALDO1 Protein, Human (HEK293, His) is the recombinant human-derived TALDO1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TALDO1 Protein, Human (HEK293, His) is 337 a.a., with molecular weight of ~38.0 kDa.

TALDO1 蛋白是磷酸戊糖途径中的关键酶，催化非氧化相的限速步骤。该酶促进景天庚酮糖 7-磷酸和 D-甘油醛 3-磷酸可逆转化为赤藓糖 4-磷酸和 β-D-果糖 6-磷酸。通过调节戊糖磷酸途径代谢物的流动，TALDO1 在生成 5-磷酸核糖和 NADPH 方面发挥着至关重要的作用，这两种物质分别对于核苷酸生物合成和细胞氧化还原平衡至关重要。此外，TALDO1 通过改变其在细胞核和细胞质之间的亚细胞定位而表现出额外的调节功能，表明它参与各种代谢途径的协调。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

HEK293

C-6*His

P37837 (M1-K337)

6888  [NCBI]

MSSSPVKRQRMESALDQLKQFTTVVADTGDFHAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGRKLGGSQEDQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGISKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPLEDPGVKSVTKIYNYYKKFSYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLQDNAKLVPVLSAKAAQASDLEKIHLDEKSFRWLHNEDQMAVEKLSDGIRKFAADAVKLERMLTERMFNAENGK

Approximately 38.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 10% Glycerol, pH 8.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.