TALDO1 - transaldolase 1 Gene

中文名称：转醛酶 1

种属: Homo sapiens

同用名: TAL; TALH; TAL-H; TALDOR

基因 ID: 6888 | 基因类型: protein coding

关于 TALDO1

Cytogenetic location: 11p15.5 Genomic coordinates (GRCh38): 11:747,464-765,012 (from NCBI)

This gene has 9 transcripts (splice variants), 206 orthologues and is associated with 3 phenotypes. Ubiquitous expression in bone marrow (RPKM 165.6), esophagus (RPKM 127.9) and 25 other tissues.

功能概要

转醛醇酶 1 是非氧化戊糖磷酸途径的关键酶，为核酸合成提供核糖 5-磷酸，为脂质生物合成提供 NADPH。该途径还可以将谷胱甘肽维持在还原状态，从而保护巯基和细胞完整性免受氧自由基的侵害。转醛醇酶 1 的功能基因位于 11 号染色体上，在 1 号染色体上发现了一个假基因，但图谱位置存在冲突。该基因的第二个和第三个外显子是通过插入逆转录转座因子而形成的。该基因被认为与多发性硬化症有关。[RefSeq 提供，2008 年 7 月]

Transaldolase 1 is a key Enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]

TALDO1 基因产物(1)

mRNA	Protein	Name
NM_006755.2	NP_006746.1	transaldolase

TALDO1 蛋白结构

TAL_FSA

0
100
200
300
337 a.a.

蛋白主名

其他名称

transaldolase

dihydroxyacetone transferase

重组 TALDO1 蛋白

目录号	产品名	蛋白编号	纯度
HY-P71351	TALDO1 Protein, Human (HEK293, His)	P37837 (M1-K337)	≥95%

关联疾病

疾病名称

别名

Transaldolase Deficiency

Taldo Deficiency	TALDOD
Eyaid Syndrome	Deficiency Of Transaldolase

Ribose 5-Phosphate Isomerase Deficiency

RPIAD	Deficiency Of Ribose-5-Phosphate Isomerase
Ribose-5-P Isomerase Deficiency	Ribose-5-Phosphate Isomerase Deficiency

Multiple Sclerosis

MS	Multiple Sclerosis, Susceptibility To
Disseminated Sclerosis	Multiple Sclerosis, Disease Progression, Modifier Of
Insular Sclerosis	Multiple Sclerosis Modifier Of Disease Progression
Multiple Sclerosis, Susceptibility To 1	Multiple Sclerosis, Susceptibility To, 1
Multiple Sclerosis 1	Generalized Multiple Sclerosis
Multiple Sclerosis Variant	Multiple Sclerosis Susceptibility To
Cerebrospinal Sclerosis	Generalised Multiple Sclerosis
Ms - [Multiple Sclerosis]	Disseminated Cerebrospinal Sclerosis
Disseminated Multiple Sclerosis	Disseminated Nervous System Myelosclerosis
Multiple Cerebrospinal Sclerosis	Multiple Combined Sclerosis
Multiple Sclerosis Generalised	Disseminated Brain Sclerosis
Disseminated Spinal Sclerosis	Insular Brain Sclerosis
Miliary Brain Sclerosis	Multiple Combined Sclerosis Of Spinal Cord
Multiple Ascending Sclerosis	Multiple Brain Sclerosis
Multiple Sclerosis Of Brain Stem	Multiple Sclerosis Of The Brain Stem
Multiple Sclerosis Of Cord	Sclérose En Plaques
Plaque Sclerosis	Multiple Sclerosis Of The Spinal Cord

Hypomagnesemia 5, Renal, With Or Without Ocular Involvement

Fhhnc With Severe Ocular Involvement	Renal Hypomagnesemia 5 With Ocular Involvement
Meier Blumberg Imahorn Syndrome	HOMG5
Hypomagnesemia, Renal, With Ocular Involvement	Hypomagnesemia 5, Renal, With Ocular Involvement
Familial Hypomagnesemia With Hypercalciuria, Nephrocalcinosis And Severe Ocular Involvement	Hypercalciuria-Bilateral Macular Coloboma Syndrome
Meier-Blumberg-Imahorn Syndrome	Hypomagnesemia, Familial, With Hypercalciuria, Nephrocalcinosis, And Severe Ocular Involvement
Macular Coloboma, Bilateral, With Hypercalciuria	Bilateral Macular Coloboma With Hypercalciuria
Idiopathic Hypercalciuria With Bilateral Macular Colobomata	Primary Hypomagnesemia With Hypercalciuria And Nephrocalcinosis With Severe Ocular Involvement
Hypomagnesemia 5	Hypomagnesemia 5 Renal With Ocular Involvement
Hypomagnesemia Renal With Ocular Involvement	Macular Coloboma Bilateral With Hypercalciuria
Hypomagnesemia, Type 5, Renal, With Ocular Involvement

Liver Cirrhosis

Cirrhosis	Cirrhosis Of Liver
CIRRH	Cryptogenic Cirrhosis
Cirrhosis, Cryptogenic	Cirrhosis Nos

Cutis Laxa

Generalized Elastolysis	Loose Skin
Dermatolysis	Dermatomegaly
Cutis Laxa Syndrome

Senile Cataract

Esophagus Sarcoma

Esophageal Sarcoma

Pancytopenia

Heart Disease

Heart Failure	Congenital Heart Disease
Heart Diseases	Congenital Heart Defects
Congenital Heart Defect	Heart Malformation
Congenital Anomaly Of Heart	Heart Defect
Heart-Congenital Defect	Congenital Heart Disorder
Heart Defects Congenital	Heart Defects, Congenital
Heart Defects	Heart Disease, Congenital
Disease, Heart, Congenital	Congestive Heart Failure

Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis	ALS
Lou Gehrig Disease	Amyotrophic Lateral Sclerosis Type 1
Charcot Disease	ALS1
Amyotrophic Lateral Sclerosis, Susceptibility To	Fals
Lou Gehrig'S Disease	Mnd
Motor Neuron Disease	Familial Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 1, Familial	Amyotrophic Lateral Sclerosis 1, Autosomal Dominant
Motor Neuron Disease, Bulbar	Motor Neurone Disease
Amyotrophic Lateral Sclerosis With Dementia	Dementia With Amyotrophic Lateral Sclerosis
Motor Neuron Disease, Amyotrophic Lateral Sclerosis	Sclerosis, Lateral, Amyotrophic
Sclerosis, Lateral, Amyotrophic, Type 1	Amyotrophic Sclerosis
Als - [Amyotrophic Lateral Sclerosis]	Wasting Palsy
Amyotrophic Paralysis	Amyotrophy Lateral Sclerosis
Wasting Paralysis	Spinal Progressive Amyotrophy
Progressive Atrophic Paralysis

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-159130	AO-022		/	否
HY-RS14191	TALDO1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	TALDO1	RGD	RGD:620674
Macaca mulatta	TALDO1	VGNC	VGNC:78096
Mus musculus	TALDO1	MGD	MGI:1274789
Bos taurus	TALDO1	VGNC	VGNC:35590
Felis catus	TALDO1	VGNC	VGNC:65947
Others	TALDO1	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

TALDO1 - transaldolase 1 Gene

关于 TALDO1

功能概要

TALDO1 基因产物(1)

TALDO1 蛋白结构

重组 TALDO1 蛋白

关联疾病

直系同源

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TALDO1 - transaldolase 1 Gene

关于 TALDO1

功能概要

TALDO1 基因产物(1)

TALDO1 蛋白结构

重组 TALDO1 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z