TFF1 蛋白, Mouse (HEK293, His)

TFF1 protein functions as a mucous gel stabilizer, vital for fortifying the gastrointestinal mucosa against noxious agents. It contributes to the mucous layer's integrity, providing a crucial physical barrier for the gastrointestinal tract, safeguarding it from potential harm. TFF1's stabilizing role emphasizes its significance in preserving the mucosal barrier, essential for overall gastrointestinal health and protection. TFF1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived TFF1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TFF1 Protein, Mouse (HEK293, His) is 66 a.a., with molecular weight of ~15.0 kDa.

三叶因子 1 (TFF1) 蛋白可作为覆盖胃肠粘膜的粘液凝胶的稳定剂，在提供针对各种有害物质的坚固物理屏障方面发挥着至关重要的作用。通过促进粘膜层的完整性，TFF1 有助于保护胃肠道免受潜在有害物质的侵害。其稳定功能强调了其在维持粘膜屏障方面的重要性，这对于胃肠粘膜的整体健康和保护至关重要。

Measured in inhibiting cell proliferation assay using AGS human gastric adenocarcinoma cells. The ED50 for this effect is 9.665 μg/mL, corresponding to a specific activity is 1.707×10^2 units/mg.

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  Measured in inhibiting cell proliferation assay using AGS human gastric adenocarcinoma cells. The ED₅₀ for this effect is 9.665 μg/mL, corresponding to a specific activity is 1.707×10² units/mg.

Mouse

HEK293

C-6*His

Q08423 (Q22-F87)

21784  [NCBI]

QAQAQAQAQEETCIMAPRERINCGFPGVTAQQCTERGCCFDDSVRGFPWCFHPMAIENTQEEECPF

Approximately 15.0 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or PBS, pH 7.4, 8% trehalose.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.