1. 重组蛋白
  2. Cytokines and Growth Factors
  3. TNF Superfamily
  4. TNF Superfamily Ligands
  5. TL1A
  6. TL1A/TNFSF15 蛋白, Cynomolgus/Rhesus macaque (HEK293, His)

TL1A/TNFSF15 蛋白, Cynomolgus/Rhesus macaque (HEK293, His)

目录号: HY-P701047
COA 产品使用指南 技术支持

TL1A/TNFSF15 蛋白是肿瘤坏死因子家族的重要成员,对于免疫调节和细胞反应至关重要。它的研究增强了我们对免疫调节的理解,为免疫测定和治疗开发提供了潜在的应用。TL1A/TNFSF15 蛋白, Cynomolgus/Rhesus macaque (HEK293, His) 是重组的 TL1A/TNFSF15 蛋白,由 HEK293 表达,带有 N-His 标签。

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规格 价格 是否有货 数量
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2 μg ¥300 In-stock
10 μg ¥760 In-stock
20 μg ¥1200 In-stock
50 μg ¥2200 In-stock
100 μg ¥3500 In-stock
500 μg ¥12500 In-stock
1 mg ¥20000 In-stock
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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The TL1A/TNFSF15 protein is an important member of the tumor necrosis factor family and is critical for immune regulation and cellular responses. Its study enhances our understanding of immune regulation, providing potential applications for immunoassay and therapeutic development. TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque (HEK293, His) is the recombinant Rhesus Macaque, cynomolgus-derived TL1A/TNFSF15 protein, expressed by HEK293 , with N-His labeled tag.

研究背景

TL1A/TNFSF15 蛋白是肿瘤坏死因子家族的重要成员,强调了其在免疫调节和细胞反应中的重要作用。作为该家族的一部分,TL1A/TNFSF15 三聚体可能与相关蛋白具有保守的结构和功能特征,强调其参与与免疫调节相关的信号通路。肿瘤坏死因子家族的分类强调了其在更广泛的细胞因子背景下的特定名称,从而深入了解其对 T 细胞激活和共刺激的独特贡献。TL1A/TNFSF15 三聚体蛋白的研究有助于我们了解其在免疫稳态中的作用,并在各种免疫测定和治疗开发中提供潜在的应用。进一步探索 TL1A/TNFSF15 三聚体的作用有望增强我们对其对正常免疫功能和病理状况的贡献的了解。

生物活性

1.Immobilized Cynomolgus/Rhesus macaque TNFSF15, His Tag at 1 μg/mL (100 μl/well) on the plate. Dose response curve for Anti-TNFSF15 Antibody, hFc Tag with the ED50 of <6 ng/mL determined by ELISA.
2.Mouse DR3 (HY-P700707), His Tag immobilized on CM5 Chip can bind Cynomolgus/Rhesus macaque TNFSF15, His Tag with an affinity constant of 5.117 nM as determined in SPR assay.

  • Mouse DR3(HY-P700707), His Tag immobilized on CM5 Chip can bind Cynomolgus/Rhesus macaque TNFSF15, His Tag with an affinity constant of 5.117 nM as determined in SPR assay.
种属

Rhesus Macaque; Cynomolgus

表达系统

HEK293

标签

N-His

蛋白编号

F6S8F9-1/A0A2K5UA22 (L72-L251)

基因 ID
蛋白结构
N-term
His
TL1A (L72-L251)
Accession # F6S8F9-1/A0A2K5UA22
C-term
中文名
TL1A 蛋白/肿瘤坏死因子SF15 蛋白
同用名
TL1A; VEGI-251; TNFSF15; TL1; VEGI; VEGI192A; TNF superfamily member 15
氨基酸序列

LKGQEFAPSHQQVYAPLRADGDKPRAHLTVVRQTPTQHLKNQFPALHWEHELGLAFTKNRMNYTNKFLLIPESGDYFVYSQVTFRGMTSECSEIRQAGRPNKPDSITVVITKVTDSYPEPTQLLMGTKSVCEVGSNWFQPIYLGAMFSLQEGDKLMVNVSDISLVDYTKEDKTFFGAFLL

分子量

Approximately 24-35 kDa due to the glycosylation.

纯度
  • Greater than 95% as determined by reducing SDS-PAGE.
性状

无菌粉末

组分

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4-8.0). Normally 8% trehalose is added as protectant before lyophilization.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque (HEK293, His)
目录号:
HY-P701047
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