TL1A/TNFSF15 蛋白, Human (161a.a, HEK293, His)

TL1A/TNFSF15 Protein, the receptor for TNFRSF25 and TNFRSF6B, activates NF-kappa-B and promotes caspase activation, leading to apoptosis. It also inhibits vascular endothelial growth and angiogenesis in vitro. TL1A/TNFSF15 Protein, Human (HEK293, His) is the recombinant human-derived TL1A/TNFSF15 protein, expressed by HEK293, with N-His labeled tag. The total length of TL1A/TNFSF15 Protein, Human (HEK293, His) is 161 a.a., with molecular weight of ~20-26 KDa.

TL1A/TNFSF15 蛋白作为 TNFRSF25 和 TNFRSF6B 的受体，促进 NF-κ-B 的激活，并促进 Caspases 的激活，导致细胞凋亡。此外，它在体外对血管内皮生长和血管生成具有抑制作用。

Measured by its ability to induce apoptosis of TF-1 human erythroleukemic cells. The ED₅₀ for this effect is 3.851 ng/mL, corresponding to a specific activity is 2.596×10⁵ units/mg.

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  Measured by its ability to induce apoptosis of TF 1 human erythroleukemic cells. The ED₅₀ for this effect is 3.851 ng/mL, corresponding to a specific activity is 2.596×10⁵ units/mg.

Human

HEK293

N-His

O95150-1 (D91-L251)

9966

DGDKPRAHLTVVRQTPTQHFKNQFPALHWEHELGLAFTKNRMNYTNKFLLIPESGDYFIYSQVTFRGMTSECSEIRQAGRPNKPDSITVVITKVTDSYPEPTQLLMGTKSVCEVGSNWFQPIYLGAMFSLQEGDKLMVNVSDISLVDYTKEDKTFFGAFLL

Approximately 20-26 kDa.

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.