TM2D1 蛋白, Human (HEK293, Fc)

The TM2D1 protein may be involved in amyloid beta-induced apoptosis by interacting with beta-APP42, especially amyloid beta protein 42 (APP beta-APP42). This suggests a role in molecular pathways associated with amyloid-induced cell death. TM2D1 Protein, Human (HEK293, Fc) is the recombinant human-derived TM2D1 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of TM2D1 Protein, Human (HEK293, Fc) is 81 a.a., with molecular weight of 45-60 KDa.

TM2D1 蛋白被认为通过与 beta-APP42 相互作用，特别是与淀粉样蛋白 42 (APP beta-APP42) 相互作用，可能参与淀粉样蛋白 β 诱导的细胞凋亡。这意味着 TM2D1 在与淀粉样蛋白诱导的细胞死亡相关的分子途径中发挥作用，特别是通过其与 β-APP42 蛋白的关联。这种相互作用的精确机制和后果仍然是人们感兴趣的领域，突显了 TM2D1 可能参与与淀粉样蛋白 β 信号传导和细胞凋亡相关的细胞过程。

Human

HEK293

C-mFc

Q9BX74/NP_114416.1 (T38-G118)

83941  [NCBI]

TSAGGEESLKCEDLKVGQYICKDPKINDATQEPVNCTNYTAHVSCFPAPNITCKDSSGNETHFTGNEVGFFKPISCRNVNG

Approximately 45-60 kDa band in SDS-PAGE under reducing conditions due to the glycosylation.

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  Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.