TMED4 蛋白, Human (HEK293, His)

The TMED4 protein is complexly involved in vesicular protein trafficking in the early secretory pathway, which is critical for targeting and maintenance of the Golgi apparatus. Its involvement extends to the biosynthesis of secretions, emphasizing its role in processing. TMED4 Protein, Human (HEK293, His) is the recombinant human-derived TMED4 protein, expressed by HEK293 , with C-His labeled tag. The total length of TMED4 Protein, Human (HEK293, His) is 165 a.a., with molecular weight of ~23 kDa.

TMED4 蛋白复杂地参与囊泡蛋白运输，特别是在早期分泌途径中，有助于高尔基体的靶向和维护。它的作用延伸到分泌物的生物合成，特别注重加工。此外，TMED4 参与内质网应激反应，显示出其在应激条件下细胞稳态中的重要性。此外，TMED4 有可能在热休克反应和细胞凋亡的调节中发挥作用，这表明它对囊泡运输以外的细胞过程有多方面的贡献。

Measured by its binding ability in a functional ELISA .Immobilized Human TMED4 at 2 μg/mL (100 μL/well) can bind Anti-TMED4 antibody, The ED₅₀ for this effect is 5.903 ng/mL.

Human

HEK293

C-His

Q7Z7H5 (L30-R194)

222068  [NCBI]

LYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQR

Approximately 23-24 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.