TMUB2 蛋白, Human (HEK293, His)

TMUB2 Protein is a poorly characterized TMUB1 paralog. TMUB2 is a part of various ERAD complexes. In addition, it is a component of the membrane that has transmembrane function. TMUB2 is related to TP53 protein expression. TMUB2 expression increases with age in skin, adipose tissue, blood, and brain and is associated with cancer initiation and progression. TMUB2 Protein, Human (HEK293, His) is the recombinant human-derived TMUB2 protein, expressed by HEK293 , with N-His labeled tag. The total length of TMUB2 Protein, Human (HEK293, His) is 209 a.a., with molecular weight of ~43 kDa.

含有跨膜和泛素样结构域的蛋白 2 (TMUB2) 是一种尚未充分表征的 TMUB1 旁系同源物。TMUB2 是各种 ERAD 复合物的一部分。此外，它是膜的组成部分，具有跨膜功能。TMUB2 与 TP53 蛋白表达相关。TMUB2 在皮肤、脂肪组织、血液和大脑中的表达随着年龄的增长而增加，并且与癌症的发生和进展相关^[1][2]。

Human

HEK293

N-His

Q71RG4-2/NP_803190.2 (Y37-S245)

79089  [NCBI]

YVADSGSNQLLGAIVSAGDTSVLHLGHVDHLVAGQGNPEPTELPHPSEGNDEKAEEAGEGRGDSTGEAGAGGGVEPSLEHLLDIQGLPKRQAGAGSSSPEAPLRSEDSTCLPPSPGLITVRLKFLNDTEELAVARPEDTVGALKSKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHCHRSPPGSAVPGPSASLAPSATEPPS

Approximately 43 kDa due to glycosylation

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.