1. 重组蛋白
  2. Receptor Proteins
  3. TREML1 蛋白, Human (147a.a, HEK293, His)

TREML1 蛋白, Human (147a.a, HEK293, His)

目录号: HY-P71382
产品使用指南

TREML1(骨髓细胞上表达的触发受体,如 1)是一种细胞表面受体,可能在先天性和适应性免疫反应中发挥作用。当磷酸化时,TREML1 与蛋白质 PTPN6 和 PTPN11 相互作用,表明它可能参与调节与免疫过程相关的信号通路。TREML1 蛋白, Human (147a.a, HEK293, His) 是重组的 TREML1 蛋白,由 HEK293 表达,带有 C-6*His 标签。TREML1 蛋白, Human (147a.a, HEK293, His) 全长 147 个氨基酸,分子量约为 ~20.0 kDa。

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描述

TREML1 (triggering receptor expressed on myeloid cells, like 1) is a cell surface receptor that may play a role in innate and adaptive immune responses. When phosphorylated, TREML1 interacts with the proteins PTPN6 and PTPN11, suggesting that it may be involved in regulating signaling pathways related to immune processes. TREML1 Protein, Human (147a.a, HEK293, His) is the recombinant human-derived TREML1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TREML1 Protein, Human (147a.a, HEK293, His) is 147 a.a., with molecular weight of ~20.0 kDa.

研究背景

TREML1(骨髓细胞上表达的触发受体,如 1)是一种细胞表面受体,可能在先天性和适应性免疫反应中发挥作用。当磷酸化时,TREML1 与蛋白质 PTPN6 和 PTPN11 相互作用,表明它可能参与调节与免疫过程相关的信号通路。这表明 TREML1 可能对免疫系统功能产生重大影响,并可能成为进一步研究了解免疫反应和开发治疗干预措施的目标。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

Q86YW5 (Q16-P162)

基因 ID
蛋白结构
N-term
TREML1 (Q16-P162)
Accession # Q86YW5
6*His
C-term
同用名
Trem-Like Transcript 1 Protein; TLT-1; Triggering Receptor Expressed on Myeloid Cells-Like Protein 1; TREML1; TLT1
氨基酸序列

QGIVGSLPEVLQAPVGSSILVQCHYRLQDVKAQKVWCRFLPEGCQPLVSSAVDRRAPAGRRTFLTDLGGGLLQVEMVTLQEEDAGEYGCMVDGARGPQILHRVSLNILPPEEEEETHKIGSLAENAFSDPAGSANPLEPSQDEKSIP

分子量

Approximately 20.0 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

TREML1 Protein, Human (147a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
TREML1 Protein, Human (147a.a, HEK293, His)
目录号:
HY-P71382
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