1. 重组蛋白
  2. Others
  3. Tubby 蛋白, Human (His)

Tubby 蛋白, Human (His)

目录号: HY-P701073
产品使用指南

Tubby 参与 G 蛋白偶联受体信号传导,与膜上的磷脂酰肌醇 4,5-二磷酸结合,可能在核转录调节中发挥作用。可能参与下丘脑重量调节并有助于凋亡细胞的吞噬作用。与 GNAQ 和 TULP1 相互作用。Tubby 蛋白, Human (His) 是重组的 管状蛋白,由 E. coli 表达,带有 N-His 标签。Tubby 蛋白, Human (His) 全长 506 个氨基酸,分子量为 56.74 kDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

Tubby, implicated in G protein-coupled receptor signaling, binds phosphatidylinositol 4,5-bisphosphate on membranes and may play a role in nuclear transcription regulation. Potentially involved in hypothalamic weight regulation and contributes to phagocytosis of apoptotic cells. Interacts with GNAQ and TULP1. Tubby Protein, Human (His) is the recombinant human-derived Tubby protein, expressed by E. coli , with N-His labeled tag. The total length of Tubby Protein, Human (His) is 506 a.a., with molecular weight of 56.74 kDa.

研究背景

Tubby 蛋白在异三聚体 G 蛋白偶联受体启动的信号转导途径中发挥作用,证明对含有磷脂酰肌醇 4,5-二磷酸的膜有亲和力。此外,Tubby 蛋白在体外表现出 DNA 结合能力,并可能在细胞核内的转录调控中发挥作用。提出了其参与下丘脑体重控制的意义。此外,Tubby 蛋白有助于刺激吞噬作用,特别是在凋亡的视网膜色素上皮 (RPE) 细胞和巨噬细胞中。它与 GNAQ 和 TULP1 的相互作用强调了它在细胞过程中的多方面作用。

种属

Human

表达系统

E. coli

标签

N-His

蛋白编号

P50607-1 (M1-E506)

基因 ID

/

蛋白结构
N-term
His
Tubby (M1-E506)
Accession # P50607-1
C-term
同用名
Tubby protein homolog; TUB; RD5; RDOB
分子量

56.74 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Tubby Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Tubby Protein, Human (His)
目录号:
HY-P701073
需求量: