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  3. UCMA 蛋白, Human

UCMA 蛋白, Human

目录号: HY-P71413
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UCMA 蛋白是成骨分化复杂控制的关键调节因子,特别是在胎儿软骨周围和软骨-骨界面处。它的参与表明在负调节骨软骨前体细胞分化中发挥着至关重要的作用。UCMA 蛋白, Human 是重组的 UCMA 蛋白,由 E. coli 表达,不带标签。UCMA 蛋白, Human 全长 74 个氨基酸,分子量约为 ~14.0 kDa。

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描述

UCMA proteins are key regulators of the complex control of osteogenic differentiation, particularly in the fetal cartilage periphery and at the cartilage-bone interface. Its involvement suggests a crucial role in negatively regulating osteochondral precursor cell differentiation. UCMA Protein, Human is the recombinant human-derived UCMA protein, expressed by E. coli , with tag free. The total length of UCMA Protein, Human is 74 a.a., with molecular weight of ~14.0 kDa.

研究背景

UCMA 蛋白在成骨分化的复杂调节中发挥着潜在的关键作用,特别是在胎儿软骨的周边区域和软骨-骨界面处。它的参与表明在对骨软骨前体细胞的分化过程施加负控制方面发挥着至关重要的作用。UCMA 在这些特定解剖区域内的调节影响强调了其在调节细胞分化的微妙平衡方面的重要性,对骨骼发育和体内平衡具有潜在影响。揭示 UCMA 对成骨分化发挥负控制作用的精确机制,可以为其功能意义提供有价值的见解,并有助于更深入地了解控制骨骼组织发育和维持的分子途径。

种属

Human

表达系统

E. coli

标签

Tag Free

蛋白编号

Q8WVF2 (S65-T138)

基因 ID
蛋白结构
N-term
UCMA (S65-T138)
Accession # Q8WVF2
C-term
同用名
Unique cartilage matrix-associated protein; UCMA; Gla-rich protein; C10orf49
氨基酸序列

SPKSRDEVNVENRQKLRVDELRREYYEEQRNEFENFVEEQNDEQEERSREAVEQWRQWHYDGLHPSYLYNRHHT

分子量

Approximately 14.0 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

UCMA Protein, Human 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
UCMA Protein, Human
目录号:
HY-P71413
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