UMP-CMP kinase/CMPK1 蛋白, Human (sf9, His)

The UMP-CMP kinase (CMPK1) protein utilizes ATP as a phosphate donor to catalyze the phosphorylation of pyrimidine nucleoside monophosphate, thereby playing a key role in cellular processes. This enzymatic activity is integral to the de novo biosynthesis of pyrimidine nucleotides and contributes to the synthesis of important cellular building blocks. UMP-CMP kinase/CMPK1 Protein, Human (sf9, His) is the recombinant human-derived UMP-CMP kinase/CMPK1 protein, expressed by Sf9 insect cells , with N-His labeled tag.

UMP-CMP 激酶，也称为 CMPK1，是一种利用 ATP 作为磷酸供体催化嘧啶核苷单磷酸磷酸化的关键酶。这种酶活性在嘧啶核苷酸从头生物合成中具有重要意义，代表了必需细胞成分合成的关键步骤。在此过程中，CMPK1 优先选择尿苷单磷酸 (UMP) 和胞苷单磷酸 (CMP) 作为磷酸盐受体。此外，CMPK1 显示出广泛的核苷二磷酸激酶活性，强调其在催化不同核苷二磷酸之间的磷酸基团转移方面的多功能性。CMPK1 的多方面功能强调了其在细胞核苷酸代谢中的关键作用及其对各种细胞过程的潜在影响。参考资料：所提供的信息基于截至 2022 年 1 月的一般知识，未引用具体参考资料。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

Sf9 insect cells

N-His

P30085-1 (M1-G196)

51727  [NCBI]

Approximately 27 kDa

Greater than 95% as determined by reducing SDS-PAGE

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris, 500 mM Nacl, pH 7.4, 10% glycerol

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.