1. 重组蛋白
  2. CD Antigens Receptor Proteins Biotinylated Proteins
  3. Endothelial cell CD Proteins
  4. U-PAR/CD87
  5. uPAR 蛋白, Mouse (HEK293, His-Avi)

uPAR 蛋白, Mouse (HEK293, His-Avi)

目录号: HY-P700849
产品使用指南

uPAR 蛋白作为尿激酶纤溶酶原激活剂的受体,促进纤溶酶形成和信号转导激活。它与 SRPX2 相互作用并形成单体。uPAR 还与 MRC2 和 SORL1 相互作用,减少 PLAUR 内化。此外,PLAUR-PLAU-SERPINE1 复合物与 SORL1 相互作用。uPAR 蛋白, Mouse (HEK293, His-Avi) 是重组的 uPAR 蛋白,由 HEK293 表达,带有 C-Avi, C-His 标签。uPAR 蛋白, Mouse (HEK293, His-Avi) 全长 275 个氨基酸,分子量为 50-65 kDa。

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描述

The uPAR protein acts as a receptor for urokinase plasminogen activator, facilitating plasmin formation and signal transduction activation. It interacts with SRPX2 and forms a monomer. uPAR also interacts with MRC2 and SORL1, reducing PLAUR internalization. Additionally, the PLAUR-PLAU-SERPINE1 complex interacts with SORL1. uPAR Protein, Mouse (HEK293, His-Avi) is the recombinant mouse-derived uPAR protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of uPAR Protein, Mouse (HEK293, His-Avi) is 275 a.a., with molecular weight of 50-65 kDa.

研究背景

uPAR 蛋白作为尿激酶纤溶酶原激活剂的受体发挥作用,在纤溶酶的定位和促进形成中起着至关重要的作用。此外,它介导 U-PA 的信号转导激活作用,与蛋白水解无关。它主要作为单体存在,并通过其 UPAR/Ly6 结构域与 SRPX2 相互作用。uPAR 还与 MRC2 和 SORL1 相互作用,后者相互作用减少 PLAUR 内化。此外,由PLAUR-PLAU-SERPINE1组成的三元复合物也与SORL1相互作用。

种属

Mouse

表达系统

HEK293

标签

C-Avi;C-His

蛋白编号

P35456-1 (L24-G298)

基因 ID

/

蛋白结构
N-term
uPAR (L24-G298)
Accession # P35456-1
His-Avi
C-term
同用名
U-PAR; uPAR; CD87; PLAUR; MO3; UPAR
分子量

50-65 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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uPAR Protein, Mouse (HEK293, His-Avi)
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HY-P700849
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