UPK2 蛋白, Human (HEK293, His)

UPK2 is a key component of the asymmetric unit membrane (AUM), a specialized biofilm made by terminally differentiated urothelial cells. Its presence suggests a potentially critical role in the complex regulation of AUM assembly. UPK2 Protein, Human (HEK293, His) is the recombinant human-derived UPK2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of UPK2 Protein, Human (HEK293, His) is 130 a.a., with molecular weight of ~27.0 kDa.

UPK2 蛋白是不对称单位膜 (AUM) 的重要组成部分，这是一种由完全分化的尿路上皮细胞复杂发育而成的特殊生物膜。它在调节 AUM 组装中的潜在参与强调了它在维持尿路上皮细胞的结构完整性和特殊功能方面的重要性。通过与 uroplakin-1a (UPK1A) 相互作用，UPK2 形成分子网络的一部分，该分子网络可能有助于形成 AUM 的独特特性。这种关联强调了 UPK2 和 UPK1A 之间复杂的相互作用，揭示了它们在终末分化尿路上皮细胞的复杂生物学中的合作作用（通过相似性）。

Human

HEK293

C-6*His

O00526 (D26-G155)

7379  [NCBI]

DFNISSLSGLLSPALTESLLVALPPCHLTGGNATLMVRRANDSKVVTSSFVVPPCRGRRELVSVVDSGAGFTVTRLSAYQVTNLVPGTKFYISYLVKKGTATESSREIPMSTLPRRNMESIGLGMARTGG

Approximately 27.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.