vacA 蛋白, Helicobacter pylori (His)

The VacA protein takes center stage, demonstrating its unique ability to induce vacuole formation in eukaryotic cells, affecting cell morphology. This process involves the formation of vacuoles, highlighting the role of VacA as a key regulator of cell structure. vacA Protein, Helicobacter pylori (His) is the recombinant vacA protein, expressed by E. coli , with N-6*His labeled tag. The total length of vacA Protein, Helicobacter pylori (His) is 209 a.a., with molecular weight of 26.6 kDa.

VacA 蛋白因其在真核细胞中诱导空泡形成的独特能力而占据中心地位，展示了其对细胞形态的强大影响。这一过程的特点是细胞内液泡的形成，反映了 VacA 作为细胞结构关键调节剂的作用。除了对细胞形态的影响外，VacA 还与引起溃疡和胃部病变有关，这强调了其在胃部疾病发病机制中的重要作用。空泡形成和促进胃部病变的双重作用使 VacA 成为一种关键的毒力因子，揭示了其在胃病理学背景下细菌病原体和宿主细胞之间复杂相互作用中的作用。

Others

E. coli

N-6*His

P55981 (T37-N245)

/

26.6 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.22 μm filtered solution of 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.