2. 重组蛋白
  3. CD Antigens
  4. Stem Cell CD Proteins Endothelial cell CD Proteins
  5. VCAM-1/CD106
  6. VCAM-1/CD106 蛋白, Mouse (HEK293, His-Fc)

VCAM-1/CD106 蛋白, Mouse (HEK293, His-Fc)

目录号: HY-P73469
产品使用指南

VCAM-1 蛋白是免疫球蛋白超家族的成员。可以作为毛细血管形成和肝纤维化的调节剂，能够促进肝纤维化。VCAM-1 蛋白 在免疫应答和炎症反应中发挥重要作用。VCAM-1/CD106 蛋白, Mouse (HEK293, His-Fc) 是重组的 VCAM-1/CD106 蛋白，由 HEK293 表达，带有 C-hFc, C-His 标签。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

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描述

VCAM-1 protein is a member of the immunoglobulin superfamily.It can act as a regulator of capillary formation and liver fibrosis, and can promote liver fibrosis.VCAM-1 Protein plays an important role in immune response and inflammatory response.VCAM-1/CD106 Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived VCAM-1/CD106 protein, expressed by HEK293 , with C-hFc, C-His labeled tag.
研究背景

VCAM-1 Protein 通过结合 α4β1 整合素来支持白细胞粘附，对炎症期间单核细胞和淋巴细胞的募集至关重要[1][5]。VCAM-1 Protein是肝窦内皮细胞(LSEC) 毛细血管形成和肝纤维化的调节剂。VCAM-1 Protein 能激活 Yes-相关蛋白1 通路并诱导HSC 中的纤维化表型[2]。VCAM-1 Protein 通过抑制效应 T 细胞凋亡来导致持续性炎症[3]。VCAM-1 Protein 在调节针对病毒感染的免疫反应和炎症反应方面的发挥重要作用[4]。VCAM-1 蛋白是平滑肌细胞迁移所必需的，靶向 VCAM-1 表达可有效预防和治疗动脉粥样硬化和再狭窄[5]。
种属

Mouse
表达系统

HEK293
标签

C-hFc;C-His
蛋白编号

Q3UPN1 (M1-E698)
基因 ID
蛋白结构
N-term
VCAM-1 (M1-E698)
Accession # Q3UPN1
hFc-His
C-term
同用名
Vascular Cell Adhesion Protein 1; VCAM-1; INCAM-100; CD106; L1CAM
分子量

110-120 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

VCAM-1/CD106 Protein, Mouse (HEK293, His-Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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