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  3. VSIG1 蛋白, Human (HEK293, His)

VSIG1 蛋白, Human (HEK293, His)

目录号: HY-P71675
产品使用指南

VSIG1 蛋白是粘附分子 (JAM) 家族的一个成员,在正常胃和睾丸,以及胃癌、食道癌和卵巢癌中表达。VSIG1 蛋白 介导 Wnt/β-catenin 信号通路的激活,具有肿瘤抑制功能,降低肿瘤细胞的增殖和迁移能力。VSIG1 蛋白, Human (HEK293, His) 是重组的 VSIG1 蛋白,由 HEK293 表达,带有 N-His 标签。

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描述

VSIG1 Protein is a member of the adhesion molecule (JAM) family and is expressed in the normal stomach and testes, as well as in cancers of the stomach, esophagus, and ovary. VSIG1 Protein mediates the activation of Wnt/尾-catenin signaling pathway, which has tumor inhibition function and reduces the proliferation and migration ability of tumor cells. VSIG1 Protein, Human (HEK293, His) is the recombinant human-derived VSIG1 protein, expressed by HEK293 , with N-His labeled tag.

研究背景

VSIG1 是粘附分子 (JAM) 家族的一个成员,在正常胃和睾丸,以及胃癌、食道癌和卵巢癌中表达。VSIG1 介导 Wnt/β-catenin 信号通路的激活,作为胃癌上皮-间质转化的新靶点。VSIG1 具有肿瘤抑制功能,降低肿瘤细胞的增殖和迁移能力。

种属

Human

表达系统

HEK293

标签

N-His

蛋白编号

Q86XK7-1 (V22-E232)

基因 ID
蛋白结构
N-term
His
VSIG1 (V22-E232)
Accession # Q86XK7-1
C-term
同用名
Cell surface A33 antigen; ChT1 thymocyte antigen; Glycoprotein A34; GPA34; MGC44287; OTTHUMP00000023820
氨基酸序列

VQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEPISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPE

分子量

Approximately 26.4 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

VSIG1 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
VSIG1 Protein, Human (HEK293, His)
目录号:
HY-P71675
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