VSIG1 - V-set and immunoglobulin domain containing 1 Gene

中文名称：含 V 组和免疫球蛋白结构域 1

种属: Homo sapiens

同用名: GPA34; dJ889N15.1; 1700062D20Rik

关于 VSIG1

功能概要

该基因编码连接粘附分子 (JAM) 家族的成员。编码的蛋白质在 N 端区域包含多个糖基化位点，在 C 端区域包含多个磷酸化位点和谷氨酸/脯氨酸 (EP) 重复序列。该基因在正常胃和睾丸以及胃癌、食道癌和卵巢癌中表达。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2009 年 12 月]

This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric, esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]