1. 重组蛋白
  2. Biotinylated Proteins
  3. VSIG2 蛋白, Human (Biotinylated, HEK293, His)

VSIG2 蛋白, Human (Biotinylated, HEK293, His)

目录号: HY-P76697
产品使用指南

VSIG2 也被称为 CTXL (皮质胸腺细胞样蛋白)。VSIG2 通过 LAMTOR2 介导的 mTOR 激活促进胰腺导管腺癌的恶性进展。VSIG2 可作为肿瘤潜在生物标志物或治疗靶点。VSIG2 蛋白, Human (Biotinylated, HEK293, His) 是重组的 VSIG2 蛋白,由 HEK293 表达,带有 C-His 标签。VSIG2 蛋白, Human (Biotinylated, HEK293, His) 全长 220 个氨基酸,分子量约为 ~24.6 kDa。

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描述

VSIG2 is also known as CTXL (cortical thymocyte like-protein). VSIG2 promotes malignant progression of pancreatic ductal adenocarcinoma through LAMtor2-mediated mTOR activation. VSIG2 can be used as a potential biomarker or therapeutic target for tumors. VSIG2 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived VSIG2 protein, expressed by HEK293 , with C-His labeled tag.

研究背景

V-set and immunoglobulin domain-containing protein 2 也称为皮质胸腺细胞样蛋白、CT 样蛋白和VSIG2,是一种单代 I 型膜蛋白。VSIG2 在胃和结肠中高表达,在膀胱和肺中表达较弱。VSIG2 与结肠癌 (COAD) 的免疫侵袭和抗原呈递相关,它可以作为 COAD 的潜在生物标志物或治疗靶点。VSIG2 通过 LAMTOR2 介导的 mTOR 激活促进胰腺导管腺癌的恶性进展。VISG2 与多种疾病相关,在Fuchs 内皮性角膜营养不良 (FECD) 患者的角膜样本中,在肠易激综合征 (IBS-D) 患者的肠道活检中,在急性小管损伤和间质纤维化/小管萎缩患者的血浆中,以及在突发心力衰竭患者的血浆中,VSIG2 被发现显著上调。

种属

Human

表达系统

HEK293

标签

C-His

蛋白编号

Q96IQ7-1 (V24-A243)

基因 ID
蛋白结构
N-term
VSIG2 (V24-A243)
Accession # Q96IQ7-1
His
C-term
同用名
V-Set and Immunoglobulin Domain-Containing Protein 2; CT-Like Protein; CTH; CTXL
分子量

Approximately 24.6 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

VSIG2 Protein, Human (Biotinylated, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
VSIG2 Protein, Human (Biotinylated, HEK293, His)
目录号:
HY-P76697
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