2. Antibody-drug Conjugate/ADC Related Cytoskeleton Cell Cycle/DNA Damage Protein Tyrosine Kinase/RTK
  3. Antibody-Drug Conjugates (ADCs) Microtubule/Tubulin c-Met/HGFR
  4. REGN5093-M114

REGN5093-M114 是一种双特异性抗体-药物偶联物 (ADC)，靶向 MET 受体酪氨酸激酶的两个表位，抑制 NSCLC 细胞增殖，在小鼠模型中表现出抗肿瘤活性。REGN5093-M114 由人单克隆抗 MET 抗体 Davutamig (HY-P990073) 和抑制微管蛋白的连接子-有效载荷 (HY-148528) 组成。

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REGN5093-M114 Chemical Structure

REGN5093-M114 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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REGN5093-M114 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

REGN5093-M114 is a bispecific antibody-drug conjugate (ADC) that targets two epitopes of the MET receptor tyrosine kinase inhibits the proliferation of NSCLC cells, exhibits antitumor efficacy in mouse models. REGN5093-M114 is composed of the human monoclonal anti-MET antibody Davutamig (HY-P990073) and the tubulin-inhibiting linker-payload (HY-148528)[1].

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

REGN5093-M114 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

REGN5093-M114Antibody-Drug Conjugates (ADCs)Microtubule/Tubulinc-Met/HGFRAntibody-Drug ConjugatesNSCLCInhibitorinhibitorinhibit

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目录号：
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