1. Others Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease Cell Cycle/DNA Damage Autophagy
  2. Isotope-Labeled Compounds RAR/RXR PPAR Endogenous Metabolite Autophagy
  3. Retinoic acid-d3-1

Retinoic acid-d3-1  (Synonyms: Vitamin A acid-d3-1; all-trans-Retinoic acid-d3-1; ATRA-d3-1)

目录号: HY-14649S6
产品使用指南

Retinoic acid-d3-1 是 Retinoic acid (HY-14649) 的氘代物。 Retinoic acid 是维生素 A 的代谢产物,在细胞生长,分化和器官发生中起重要作用。Retinoic acid 是 RAR 核受体的天然激动剂,对 RARα/β/γ 的 IC50 为 14 nM。 Retinoic acidPPARβ/δ 结合的 Kd 值为 17 nM。Retinoic acid 可以通过激活视黄酸受体抑制转录因子 Nrf2。

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Retinoic acid-d<sub>3</sub>-1 Chemical Structure

Retinoic acid-d3-1 Chemical Structure

CAS No. : 3041101-53-2

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生物活性

Retinoic acid-d3-1 is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[1][2][3].

分子量

303.45

Formula

C20H25D3O2

CAS 号
非标记 CAS
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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