2. 天然产物
  3. 抗生素 微生物
  4. 大环内酯类
  5. Rhizopodin

Rhizopodin是一种新的细胞抑制化合物，从黏菌Myxococcus stipitatus的培养液中分离出来。Rhizopodin能抑制各种动物细胞培养的生长，但不会杀死细胞，其ID50值为12 ~ 30 ng/ml，具体取决于细胞系。特别是类似成纤维细胞的细胞表现出典型的形态变化，细胞变大并在数小时内形成长的分支网状延伸，这些形态变化是不可逆的。Rhizopodin抑制K-562细胞中的气泡形成，可能通过与蛋白质磷酸化相互作用发挥作用。

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Rhizopodin Chemical Structure

Rhizopodin Chemical Structure

CAS No. : 150346-23-9

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Rhizopodin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Rhizopodin is a new cytostatic compound isolated from the culture fluid of the slime mold Myxococcus stipitatus. Rhizopodin inhibits the growth of various animal cell cultures without killing the cells, with an ID50 value of 12 to 30 ng/ml, depending on the cell line. In particular, fibroblast-like cells show typical morphological changes, with cells becoming larger and forming long branched reticular extensions within hours, and these morphological changes are irreversible. Rhizopodin inhibits bleb formation in K-562 cells, possibly through interaction with protein phosphorylation.

分子量

1469.83

Formula

C78H124N4O22
CAS 号
结构分类
初始来源

Myxococcus stipitatus
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Rhizopodin 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rhizopodin150346-23-9OthersInhibitorinhibitorinhibit

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