2. GPCR/G Protein Membrane Transporter/Ion Channel Neuronal Signaling Metabolic Enzyme/Protease
  3. Leukotriene Receptor Calcium Channel Endogenous Metabolite
  4. Ricinelaidic acid

Ricinelaidic acid,一种 12 羟基脂肪酸，是一种白三烯 B4 受体 (leukotriene B4 (LTB4) receptor) 拮抗剂，在猪中性粒细胞膜中的 Ki 值为 2 μ M。Ricinelaidic acid 抑制 LTB4 诱导的离体人中性粒细胞趋化性和钙通量（IC50 值分别为 10 和 7µM）。Ricinelaidic acid 抑制 LTB4 所致大鼠支气管收缩。

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Ricinelaidic acid Chemical Structure

Ricinelaidic acid Chemical Structure

CAS No. : 540-12-5

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Other Forms of Ricinelaidic acid:

Ricinelaidic acid 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Ricinelaidic acid,a 12-hydroxy fatty acid，is a leukotriene B4 (LTB4) receptor antagonist with the Ki of 2 µM in porcine neutrophil membranes. Ricinelaidic acid inhibits chemotaxis and calcium flux induced by LTB4 in isolated human neutrophils (IC50values = 10 and 7 µM, respectively). Ricinelaidic acid inhibits bronchoconstriction induced by LTB4 in rats[1].

分子量

298.46

Formula

C18H34O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ricinelaidic acid 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Ricinelaidic acid540-12-5Leukotriene ReceptorCalcium ChannelEndogenous MetaboliteCa2+ channelsCa channelsleukotriene B4 receptorisolated human neutrophilsbronchoconstriction induced by LTB4 in ratsInhibitorinhibitorinhibit

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