2. Apoptosis
  3. RIP kinase
  4. RIP2 kinase inhibitor 1

RIP2 kinase inhibitor 1 (compound 11) 是一种有效且选择性的受体相互作用蛋白 2 (RIP2) 激酶抑制剂，对 RIP2 FP 的 IC50 为 0.03μM。RIP2 kinase inhibitor 1 可用于自免疫疾病。

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RIP2 kinase inhibitor 1 Chemical Structure

RIP2 kinase inhibitor 1 Chemical Structure

CAS No. : 2380028-10-2

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RIP2 kinase inhibitor 1 相关抗体

Top Publications Citing Use of Products

查看 RIP kinase 亚型特异性产品:

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RIPK1 RIPK2 RIPK3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RIP2 kinase inhibitor 1 (compound 11) is a potent and selective receptor interacting protein 2 (RIP2) kinase inhibitor with an IC50 of 0.03 μM for RIP2 FP. RIP2 kinase inhibitor 1 is used for autoinflammatory disorders[1].

IC50 & Target

IC50: 0.03 μM (RIP2)[1]
体外研究
(In Vitro)

RIP2 kinase inhibitor 1 (compound 11) inhibits human whole blood (hWB; IC50=0.05 μM), activin receptor-like kinase 5 (ALK5; IC50>10 μM), VEGFR2 (IC50=7.94 μM), lymphocyte-specific protein tyrosine kinase (LCK; IC50=31.6 μM)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

RIP2 kinase inhibitor 1 相关抗体:
分子量

355.41

Formula

C17H17N5O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

RIP2 kinase inhibitor 1 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RIP2 kinase inhibitor 12380028-10-2RIP kinaseReceptor-interacting protein kinasesRIPKreceptorinteractingproteinRIP2autoinflammatoryInhibitorinhibitorinhibit

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