2. Metabolic Enzyme/Protease
  3. Ser/Thr Protease
  4. RIPK1-IN-26

RIPK1-IN-26 (Compound 8a) 是一种强效的受体相互作用丝氨酸/苏氨酸激酶 1 (RIPK1) 抑制剂，具有细胞抗坏死能力。RIPK1-IN-26 在小鼠中展示了良好的代谢稳定性和良好的结合特异性。RIPK1-IN-26 有望用于 PET 成像探针开发和神经退行性疾病的研究。

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RIPK1-IN-26 Chemical Structure

RIPK1-IN-26 Chemical Structure

CAS No. : 2252271-96-6

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RIPK1-IN-26 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RIPK1-IN-26 (Compound 8a) is a potent receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitor with cell anti-necroptosis potency. RIPK1-IN-26 demonstrats good metabolic stability and good binding specificity in mice. RIPK1-IN-26 is promising for research of PET imaging probe development and neurodegenerative disorders[1].

分子量

265.32

Formula

C15H20FNO2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

RIPK1-IN-26 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RIPK1-IN-262252271-96-6Ser/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasesRIPK1anti-necroptosismetabolic stabilitybinding specificitymiceneurodegenerative disordersInhibitorinhibitorinhibit

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目录号：
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