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RM 49 是 Mitomycin C (HY-13316) 的衍生物。RM 49 在 SCLC 和 NSCLC 肺癌细胞中具有细胞毒性,IC50 为 0.01-0.5 μg/mL。RM 49 与 Mitomycin C,Cisplatin (HY-17394),Carboplatin (HY-17393) 和 Doxorubicin (HY-15142) 相比,具有较高的相对抗肿瘤活性。

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RM 49 Chemical Structure

RM 49 Chemical Structure

CAS No. : 113785-48-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RM 49 is the derivative of Mitomycin C (HY-13316). RM 49 exhibits cytotoxicity in SCLC and NSCLC lung cancer cells with IC50 of 0.01-0.5 μg/mL. RM 49 exhibits high relative antitumor activity in compared with Mitomycin C, Cisplatin (HY-17394), Carboplatin (HY-17393) and Doxorubicin (HY-15142)[1].

分子量

364.35

Formula

C16H20N4O6

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
RM 49
目录号:
HY-120436
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