2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. Ro 23-3423

Ro 23-3423 是一种血栓烷合成酶抑制剂，对人血小板微粒体血栓烷合成酶的 IC50 值为 0.33 μM。Ro 23-3423 以剂量依赖性方式增加了 PGF 和 PGE2 的血浆水平，并伴随着平均全身动脉压和全身血管阻力的下降。Ro 23-3423 可用于全身麻醉的研究。

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Ro 23-3423 Chemical Structure

Ro 23-3423 Chemical Structure

CAS No. : 110996-51-5

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Ro 23-3423 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Ro 23-3423 is a thromboxane synthase inhibitor with an IC50 value of 0.33 μM for human platelet microsomal thromboxane synthase. Ro 23-3423 increases plasma levels of PGF and PGE2 in a dose-dependent manner, accompanied by a decrease in mean systemic arterial pressure and systemic vascular resistance. Ro 23-3423 can be used in the study of general anesthesia[1].

分子量

386.45

Formula

C23H22N4O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ro 23-3423 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ro 23-3423110996-51-5Prostaglandin ReceptorInhibitorsplateletsmicrosomessystemic arterial pressuregeneral anesthesiaInhibitorinhibitorinhibit

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