2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Ro 63-0563

Ro 63-0563 是一种有效的，竞争性和选择性的 5-HT6 受体拮抗剂，对大鼠和人的 5-HT6 受体的 pKi 值分别为 7.83、7.91。Ro 63-0563 对其他受体没有亲和力。

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Ro 63-0563 Chemical Structure

Ro 63-0563 Chemical Structure

CAS No. : 202466-77-1

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Ro 63-0563 相关抗体

Top Publications Citing Use of Products

查看 5-HT Receptor 亚型特异性产品:

查看所有亚型
5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ro 63-0563 is a potent, competitive and selective 5-HT6 receptor antagonist with pKi values ??of 7.83 and 7.91 for rat and human 5-HT6 receptors, respectively. Ro 63-0563 has no affinity for other receptors[1].

IC50 & Target[1]

Rat 5-HT6 Receptor

7.83 (pKi)

Human 5-HT6 Receptor

7.91 (pKi)

分子量

307.37

Formula

C13H17N5O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ro 63-0563 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ro 63-0563202466-77-15-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorCompetitiveantagonistInhibitorinhibitorinhibit

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产品名称：
Ro 63-0563
目录号：
HY-120239
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