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Rohitukine 是一种生物碱，具有具有镇痛和抗炎活性。

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Rohitukine Chemical Structure

Rohitukine Chemical Structure

CAS No. : 71294-60-5

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Rohitukine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Rohitukine is an alkaloid with analgesic and anti-inflammatory activities[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 10 μM
Compound: 5
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
[PMID: 19757855]
ASPC1 GI50
21 μM
Compound: 1
Cytotoxicity against human AsPC1 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human AsPC1 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
BXPC-3 GI50
20 μM
Compound: 1
Cytotoxicity against human BxPC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human BxPC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
Caco-2 GI50
25 μM
Compound: 1
Growth inhibition of human Caco2 cells after 48 hrs by MTT assay
Growth inhibition of human Caco2 cells after 48 hrs by MTT assay
[PMID: 29370702]
DU-145 GI50
26 μM
Compound: 1
Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
HCT-116 IC50
8.8 μM
Compound: 5
Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
[PMID: 19757855]
HEK293 GI50
> 50 μM
Compound: 1
Cytotoxicity against HEK293 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against HEK293 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
HL-60 GI50
10 μM
Compound: 1
Growth inhibition of human HL60 cells after 48 hrs by MTT assay
Growth inhibition of human HL60 cells after 48 hrs by MTT assay
[PMID: 29370702]
HL-60 GI50
10 μM
Compound: 1
Cytotoxicity against human HL60 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
HL-60 IC50
7.5 μM
Compound: 5
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
[PMID: 19757855]
Hs-578T GI50
20 μM
Compound: 1
Cytotoxicity against human Hs578T cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human Hs578T cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
K562 GI50
24 μM
Compound: 1
Cytotoxicity against human K562 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human K562 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
LNCaP GI50
30 μM
Compound: 1
Cytotoxicity against human LNCAP cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human LNCAP cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
MCF7 IC50
> 10 μM
Compound: 5
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
[PMID: 19757855]
MCF7 GI50
28 μM
Compound: 1
Growth inhibition of human MCF7 cells after 48 hrs by MTT assay
Growth inhibition of human MCF7 cells after 48 hrs by MTT assay
[PMID: 29370702]
MDA-MB-231 GI50
13 μM
Compound: 1
Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
MDA-MB-468 GI50
17 μM
Compound: 1
Cytotoxicity against human MDA-MB-468 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-468 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
MIA PaCa-2 GI50
19 μM
Compound: 1
Growth inhibition of human MIAPaCa2 cells after 48 hrs by MTT assay
Growth inhibition of human MIAPaCa2 cells after 48 hrs by MTT assay
[PMID: 29370702]
MIA PaCa-2 GI50
19 μM
Compound: 1
Cytotoxicity against human MIAPaCa2 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human MIAPaCa2 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
MOLT-4 GI50
12 μM
Compound: 1
Cytotoxicity against human MOLT4 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human MOLT4 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
NCI-H226 IC50
> 10 μM
Compound: 5
Cytotoxicity against human NCI-H226 cells after 48 hrs by MTT assay
Cytotoxicity against human NCI-H226 cells after 48 hrs by MTT assay
[PMID: 19757855]
PANC-1 GI50
22 μM
Compound: 1
Cytotoxicity against human PANC1 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human PANC1 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
PC-3 GI50
19 μM
Compound: 1
Growth inhibition of human PC3 cells after 48 hrs by MTT assay
Growth inhibition of human PC3 cells after 48 hrs by MTT assay
[PMID: 29370702]
PC-3 GI50
19 μM
Compound: 1
Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
PSN1 GI50
23 μM
Compound: 1
Cytotoxicity against human PSN1 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human PSN1 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
SF-295 GI50
27 μM
Compound: 1
Cytotoxicity against human SF295 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human SF295 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
SF-539 GI50
30 μM
Compound: 1
Cytotoxicity against human SF539 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human SF539 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
SNB-75 GI50
22 μM
Compound: 1
Cytotoxicity against human SNB75 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human SNB75 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
T47D GI50
24 μM
Compound: 1
Cytotoxicity against human T47D cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human T47D cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
THP-1 GI50
28 μM
Compound: 1
Cytotoxicity against human THP1 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human THP1 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
U-251 GI50
32 μM
Compound: 1
Cytotoxicity against human U251 cells assessed as cell growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human U251 cells assessed as cell growth inhibition after 48 hrs by MTT assay
[PMID: 27363938]
分子量

305.33

Formula

C16H19NO5
CAS 号
中文名称

罗希吐碱
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Rohitukine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rohitukine71294-60-5罗希吐碱OthersAlkaloidsanalgesicsanti-inflammatoryInhibitorinhibitorinhibit

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目录号：
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