1. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  2. ROR
  3. RORγt inverse agonist 33

RORγt inverse agonist 33 (compound (R)-D4) 是一种口服生物可利用的 RORγt 反向激动剂,其 IC50 为 21 nM。RORγt inverse agonist 33 在类风湿关节炎研究中发挥着重要作用。

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RORγt inverse agonist 33 Chemical Structure

RORγt inverse agonist 33 Chemical Structure

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  • 生物活性

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  • 参考文献

生物活性

RORγt inverse agonist 33 (compound (R)-D4) is an orally bioavailable and inverse agonists of RORγt, with the IC50 of 21 nM. RORγt inverse agonist 33 plays an important role in rheumatoid arthritis research[1].

IC50 & Target[1]

RORγt

21 nM (IC50)

分子量

487.65

Formula

C27H37NO5S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
RORγt inverse agonist 33
目录号:
HY-169952
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