ROR Inhibitors

RORγ, IC₅₀: 0.55 μM

RORγt

ROR-γ, IC₅₀: 0.19 μM (in 293 T cells)

ROR-α, IC₅₀: 7.57 μM (in 293 T cells)

RORγt

ROR-γ, EC₅₀: 2 nM

RORγ, EC₅₀: 1 μM

RORγ

ROR-γ, IC₅₀: 63.8 nM

RORγt, Ki: 3.5 nM
RORγt, IC₅₀: 17 nM

RORγ, IC₅₀: 1 μM

RORγt, IC₅₀: <30 nM

RORγt, IC₅₀: 51 nM

RORγt, Ki: 120 nM

RORγt, EC₅₀: 12 nM

RORα, EC₅₀: >10 μM

RORβ, EC₅₀: >10 μM

RORγt, IC₅₀: 5 nM

ROR-γ

RORγt

RORγt, Ki: <100 nM

RORγt, IC₅₀: 46 nM

RORγ, IC₅₀: 1.1 μM

RORγ

RORγt, IC₅₀: 21 nM

ROR-γ, EC₅₀: 12 nM

RORγ, IC₅₀: 0.21 μM

ROR-γ

RORγt, Ki: 3.5 nM
RORγt, IC₅₀: 17 nM