1. GPCR/G Protein Neuronal Signaling
  2. Cholecystokinin Receptor
  3. RP 72540

RP 72540  (Synonyms: RPR101048)

目录号: HY-100481
产品使用指南

RP 72540 是一种选择性 CCK-B 受体拮抗剂,对豚鼠大脑皮层、 大鼠大脑皮层 以及小鼠大脑 CCK-B 受体的 IC50 为 2.4、1.2 和 3.8 nM。RP 72540 可有效抑制 CCK-8 诱导的神经元放电,且以剂量依赖的方式抑制胃酸,在抗胃酸分泌研究中具有潜在应用价值。RP 72540 是研究 CCK B 受体生理功能的重要工具。

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RP 72540 Chemical Structure

RP 72540 Chemical Structure

CAS No. : 139088-45-2

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查看 Cholecystokinin Receptor 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RP 72540 is a selective CCK-B receptor antagonist, with IC50 values of 2.4, 1.2, and 3.8 nM for CCK-B receptors in the guinea pig cerebral cortex, rat cerebral cortex, and mouse brain, respectively. RP 72540 effectively inhibits CCK-8-induced neuronal firing and dose-dependently inhibits gastric acid secretion, making it potentially valuable in studies of acid secretion. RP 72540 is an important tool for investigating the physiological functions of CCK B receptors[1].

分子量

518.56

Formula

C28H30N4O6

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
RP 72540
目录号:
HY-100481
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