2. Stem Cell/Wnt
  3. PKG
  4. Rp-8-pCPT-cGMPS sodium

Rp-8-pCPT-cGMPS sodium 是 Rp-8-pCPT-cGMPS 的钠盐形式。Rp-8-pCPT-cGMPS sodium 是 cGMP 依赖性蛋白激酶 (cGK) 的抑制剂。Rp-8-pCPT-cGMPS sodium 是电压依赖性环核苷酸门控 (CNG) 通道激动剂。。

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Rp-8-pCPT-cGMPS sodium Chemical Structure

Rp-8-pCPT-cGMPS sodium Chemical Structure

CAS No. : 208445-07-2

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Other Forms of Rp-8-pCPT-cGMPS sodium:

Rp-8-pCPT-cGMPS sodium 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Rp-8-pCPT-cGMPS sodium is the sodium salt form of Rp-8-pCPT-cGMPS. Rp-8-pCPT-cGMPS is an inhibitor for cGMP-dependent protein kinase (cGK). Rp-8-pCPT-cGMPS sodium is an agonist for cyclic nucleotide-gated (CNG) channels in a voltage-dependent manner[1][2].

体内研究
(In Vivo)

Rp-8-pCPT-cGMPS sodium (5 nM，鞘内注射，每天一次，持续 3 天) 抑制 cGMP-cGKI 通路，抑制 Sprague-Dawley 大鼠模型中肿瘤细胞植入 (TCI) 诱导的热痛觉过敏和机械异常性疼痛[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Bone cancer pain induced by tumor cell implantation (TCI) in Sprague-Dawley rats[1].
Dosage: 0.5 mmol/L, 20 μL
Administration: intrathecally, once a day for 3 days
Result: Delayed and suppressed TCI-induced thermal hyperalgesia and mechanical allodynia.
分子量

525.86

Formula

C16H14ClN5NaO6PS2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Rp-8-pCPT-cGMPS sodium 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Rp-8-pCPT-cGMPS208445-07-2PKGSprague-Dawley ratshyperalgesiaallodyniabone cancer painInhibitorinhibitorinhibit

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