1. GPCR/G Protein
  2. GPR88
  3. RTI-122

RTI-122 是一种具有良好代谢稳定性(在小鼠中半衰期为 5.8 小时)和 cAMP EC50 为 11 nM 的有效 GPR88 激动剂,能够穿透血脑屏障。RTI-122 可用于与过度饮酒相关的研究。

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RTI-122 Chemical Structure

RTI-122 Chemical Structure

CAS No. : 3034664-39-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RTI-122 is a brain-penetrant and potent GPR88 agonist with good metabolic stability (half-life of 5.8 h in mice) and a cAMP EC50 of 11 nM. RTI-122 can be utilized in research on excessive drinking[1].

分子量

491.60

Formula

C29H34FN3O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
RTI-122
目录号:
HY-167856
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