2. Anti-infection
  3. Antibiotic Bacterial
  4. Rubradirin

Rubradirin 是一种多肽合成抑制剂，具有显著抗菌活性。Rubradirin 特异性作用于核糖体的 P 位 (Peptidyl site)，通过阻止依赖起始因子的 fMet-tRNAf (甲酰甲硫氨酰转运核糖核酸) 与核糖体小亚基 (30S) 和完整核糖体 (70S) 结合来干扰蛋白质合成的起始过程，同时解离已形成的起始复合物，从而发挥抑菌作用。

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Rubradirin Chemical Structure

Rubradirin Chemical Structure

CAS No. : 11031-38-2

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Rubradirin 相关抗体

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Rubradirin is a polypeptide synthesis inhibitor with significant antibacterial activity. It specifically targets the peptidyl site (P site) of the ribosome and interferes with the initiation of protein synthesis by preventing the binding of fMet-tRNAf (formylmethionyl transfer RNA) to the 30S ribosomal subunit and the complete 70S ribosome in an initiation factor-dependent manner. Additionally, it dissociates already formed initiation complexes, thereby exerting its antibacterial effect[1][2]。

分子量

998.89

Formula

C48H46N4O20
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Rubradirin 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rubradirin11031-38-2AntibioticBacterialInhibitorinhibitorinhibit

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