1. Others Membrane Transporter/Ion Channel
  2. Isotope-Labeled Compounds ASCT
  3. S-Benzyl-DL-cysteine-2,3,3-d3

S-Benzyl-DL-cysteine-2,3,3-d3 

目录号: HY-144354S
产品使用指南

S-Benzyl-DL-cysteine-2,3,3-d3 是 Benzylcysteine 的一种氘代化合物。Benzylcysteine 是 ASCT2 竞争性抑制剂,与 ASCT2 结合,表观 Ki 为 780 μM。

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S-Benzyl-DL-cysteine-2,3,3-d<sub>3</sub> Chemical Structure

S-Benzyl-DL-cysteine-2,3,3-d3 Chemical Structure

CAS No. : 51494-04-3

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生物活性

S-Benzyl-DL-cysteine-2,3,3-d3 is a deuterium labeled Benzylcysteine. Benzylcysteine is an ASCT2 inhibitor that binds to ASCT2 with an apparent Ki of 780 μM. Benzylcysteine inhibit ASCT2 function based on a competitive mechanism, indicating that Benzylcysteine binds to the substrate-binding site of ASCT2[1].

IC50 & Target

ASCT2

780 μM (Ki)

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

214.30

Formula

C10H10D3NO2S

CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献
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产品名称:
S-Benzyl-DL-cysteine-2,3,3-d3
目录号:
HY-144354S
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