2. Apoptosis
  3. Apoptosis
  4. (S)-Erypoegin K

(S)-Erypoegin K 是一种有效的抗癌剂。(S)-Erypoegin K 对 HL-60 细胞显示出有效的抗增殖活性。(S)-Erypoegin K 诱导细胞凋亡 (apoptosis)。

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(S)-Erypoegin K Chemical Structure

(S)-Erypoegin K Chemical Structure

CAS No. : 2055053-90-0

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(S)-Erypoegin K 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(S)-Erypoegin K is a potent anticancer agent. (S)-Erypoegin K shows potent anti-proliferative activity against HL-60 cells. (S)-Erypoegin K induces apoptosis[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
GCIY IC50
0.27 μM
Compound: (S)-EpK
Cytotoxicity against human GCIY cells assessed as reduction in cell viability measured after 48 hrs by MTS/CellTiter96 aqueous one solution cell proliferation assay
Cytotoxicity against human GCIY cells assessed as reduction in cell viability measured after 48 hrs by MTS/CellTiter96 aqueous one solution cell proliferation assay
[PMID: 33341500]
HL-60 IC50
90 nM
Compound: (S)-EpK
Antiproliferative activity against human HL60 cells assessed as inhibition of cell viability incubated for 48 hrs by MTS assay
Antiproliferative activity against human HL60 cells assessed as inhibition of cell viability incubated for 48 hrs by MTS assay
[PMID: 32299660]
MKN-1 IC50
0.327 μM
Compound: (S)-EpK
Cytotoxicity against human MKN-1 cells assessed as reduction in cell viability measured after 48 hrs by MTS/CellTiter96 aqueous one solution cell proliferation assay
Cytotoxicity against human MKN-1 cells assessed as reduction in cell viability measured after 48 hrs by MTS/CellTiter96 aqueous one solution cell proliferation assay
[PMID: 33341500]
体外研究
(In Vitro)

(S)-Erypoegin K (0-1 µM; 48 h)shows potent anti-proliferative activity against HL-60 cells with an IC50 of 90 nM[1].
(S)-Erypoegin K (0.1, 0.5 µM; 24 h) induces marked activation of caspase-3 and −9 in HL-60 cells in a time- and dose-dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(S)-Erypoegin K 相关抗体:
分子量

354.35

Formula

C20H18O6
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(S)-Erypoegin K 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-Erypoegin K2055053-90-0ApoptosisanticancerapoptosisHL-60 cellsanti-proliferativeInhibitorinhibitorinhibit

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