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  3. S-(+)-GABOB

S-(+)-GABOB是一种内源性配体,具有抗癫痫活性。S-(+)-GABOB是GABA的代谢产物,可能作为神经递质发挥作用。S-(+)-GABOB在与ρ(1)wild-type受体结合时表现为完全激动剂。S-(+)-GABOB在ρ(1)T244S突变体受体中则作为竞争性拮抗剂发挥作用。

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S-(+)-GABOB Chemical Structure

S-(+)-GABOB Chemical Structure

CAS No. : 7013-05-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

S-(+)-GABOB is an endogenous ligand with antiepileptic activity. S-(+)-GABOB is a metabolite of GABA and may function as a neurotransmitter. S-(+)-GABOB behaves as a full agonist when bound to the ρ(1) wild-type receptor. S-(+)-GABOB acts as a competitive antagonist in the ρ(1) T244S mutant receptor[1].

分子量

119.12

Formula

C4H9NO3

CAS 号
性状

固体

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

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参考文献

S-(+)-GABOB 相关分类

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产品名称:
S-(+)-GABOB
目录号:
HY-W050122
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