2. Inhibitory Antibodies
  3. Samalizumab

Samalizumab  (Synonyms: 沙马组单抗; ALXN 6000)

目录号: HY-P99400 纯度: 99.81%
COA

摩尔计算器

Samalizumab (ALXN 6000) 是一种人源化单克隆抗体，可特异性结合 CD200 并阻断其与 CD200 受体 (CD200R) 的连接。 Samalizumab 可用于多发性骨髓瘤和 B 细胞慢性淋巴细胞白血病的研究。

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CAS No. : 1073059-33-2

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规格 价格 是否有货 数量
1 mg ￥3000
In-stock
5 mg ￥7800
In-stock
10 mg   询价  
50 mg   询价  

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Customer Review

Samalizumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Samalizumab (ALXN 6000) is a humanized monoclonal antibody that specifically binds to CD200 and blocks its ligation to the CD200 receptor (CD200R). Samalizumab can be used for multiple myeloma and B-cell chronic lymphocytic leukemia research[1].

同型

IgG2-G4 kappa
种属

Humanized

体外研究
(In Vitro)

Samalizumab 被合理设计为具有 Ig G2/G4 恒定区，以最大限度地减少效应子功能并保护免疫细胞亚群。Samalizumab 是一种重组人源化抗 CD200 单抗，旨在消除效应子功能，特异性结合免疫检查点 CD200，阻断受体参与和信号传导，并拮抗 CD200 驱动的免疫抑制，从而发挥抗肿瘤作用免疫反应[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Samalizumab 相关抗体:
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

沙马组单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • IgG2-G4-kappa
Biological Activity
  • Immobilized CD200 Protein (His Tag), Human can bind Samalizumab. The EC50 for this effect is 1.53 ng/mL.
纯度 & 产品资料
参考文献

Samalizumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Samalizumab1073059-33-2ALXN 6000沙马组单抗ALXN6000ALXN-6000Othershumanized monoclonal antibodyCD200multiple myelomaB-cell chronic lymphocytic leukemiaInhibitorinhibitorinhibit

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