2. Anti-infection
  3. Parasite
  4. SAR 97276

SAR 97276  (Synonyms: Albitiazolium bromide)

目录号: HY-14830
产品使用指南

摩尔计算器

SAR 97276 (Albitiazolium bromide) 是一种抗疟剂。SAR 97276 可以干扰疟原虫的磷脂代谢，尤其是磷脂酰胆碱 (PC) 的生物合成。SAR 97276 通过受感染红细胞的新通透性途径 (NPP) 进入红细胞，并通过多特异性阳离子载体转运到疟原虫体内。

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SAR 97276 Chemical Structure

SAR 97276 Chemical Structure

CAS No. : 321915-72-4

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SAR 97276 相关抗体

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SAR 97276 (Albitiazolium bromide) is an antimalarial agent. SAR 97276 interfers with the phospholipid metabolism of malarial parasites, especially the biosynthesis of phosphatidylcholine (PC). SAR 97276 enters erythrocytes through the new permeability pathways (NPP) of infected erythrocytes, and is transported into the malarial parasite by a poly-specific cation carrier[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Jurkat IC50
347 μM
Compound: T3
Cytotoxicity against human Jurkat cells after 24 hrs by [3H]thymidine incorporation assay
Cytotoxicity against human Jurkat cells after 24 hrs by [3H]thymidine incorporation assay
[PMID: 23289711]
分子量

614.54

Formula

C24H42Br2N2O2S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SAR 97276 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SAR 97276321915-72-4AlbitiazoliumSAR97276SAR-97276ParasiteP. falciparumantimalarialInhibitorinhibitorinhibit

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