2. Anti-infection
  3. Antibiotic Bacterial
  4. Sarubicin B

Sarubicin B 是一种活性产物，可从链霉菌株 (Streptomyces strain) JA 2861 的培养滤液中分离出来。Sarubicin B 是一种醌类抗生素，可抑制革兰氏阳性菌，但对革兰氏阴性微生物无效。

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Sarubicin B Chemical Structure

Sarubicin B Chemical Structure

CAS No. : 84745-01-7

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Sarubicin B 相关抗体

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sarubicin B is an active product that can be isolated from the culture filtrate of a Streptomyces strain JA 2861. Sarubicin B is a quinone antibiotic that inhibit Gram-positive bacteria and not active against Gram-negative microorganisms[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
4T1 IC50
7.6 μM
Compound: 2
Cytotoxicity against mouse 4T1 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
Cytotoxicity against mouse 4T1 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
[PMID: 35213166]
A549 IC50
13.5 μM
Compound: 2
Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
[PMID: 35213166]
HCT-116 IC50
14.8 μM
Compound: 2
Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
[PMID: 35213166]
HepG2 IC50
6.3 μM
Compound: 2
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
[PMID: 35213166]
分子量

258.23

Formula

C13H10N2O4
CAS 号
结构分类
初始来源

streptomyces strain
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Sarubicin B 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sarubicin B84745-01-7AntibioticBacterialInhibitorinhibitorinhibit

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产品名称：
Sarubicin B
目录号：
HY-123436
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