2. Immunology/Inflammation
  3. Interleukin Related
  4. Satralizumab

Satralizumab  (Synonyms: 萨特利珠单抗)

目录号: HY-P99112 纯度: 99.82%
COA

摩尔计算器

Satralizumab 是一种人源化单克隆抗体，是一种有效的白细胞介素 -6 (IL-6) 抑制剂。Satralizumab 可防止褐家鼠的 dTAA 形成和发展。Satralizumab 可用于视神经脊髓炎 (NMOSD) 和降胸主动脉动脉瘤 (dTAA) 的研究。

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CAS No. : 1535963-91-7

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规格 价格 是否有货 数量
1 mg ￥2600
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5 mg ￥6500
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Satralizumab 相关抗体

Top Publications Citing Use of Products

查看 Interleukin Related 亚型特异性产品:

查看所有亚型
IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Satralizumab, a humanized monoclonal antibody, is a potent Interleukine-6 (IL-6) inhibitor. Satralizumab prevents dTAA formation and progression in rattus norvegicus. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research[1][2].

同型

Human IgG2 kappa
推荐同型对照抗体
种属

Humanized
IC50 & Target

IL-6

 

体内研究
(In Vivo)

Satralizumab (120 mg, Subcutaneously, once every 2 weeks, for 4 weeks) prevents dTAA formation and progression in rattus norvegicus[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rattus norvegicus (forty, male, 10-week-old, four equal groups)[1]
Dosage: 120 mg
Administration: Subcutaneously, once every 2 weeks, for 4 weeks
Result: Prevented dTAA (descending thoracic aorta aneurysm) formation and progression.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

萨特利珠单抗；沙利珠单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG2 kappa
纯度 & 产品资料
参考文献

Satralizumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Satralizumab1535963-91-7萨特利珠单抗沙利珠单抗Interleukin RelatedILlongitudinally extensive transverse myelitismonoclonal antibodyneuromyelitis optica spectrum disorderNMONMOSDdescending thoracic aorta aneurysmInhibitorinhibitorinhibit

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