2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. SCH 351591

SCH 351591 是一种强效、选择性和具有口服活性的磷酸二酯酶 4 (PDE4) 抑制剂，IC50 为 58 nM。SCH 351591 可以抑制所有 4 种 PDE4 亚型（A、B、C 和 D）。SCH 351591 具有用于哮喘和慢性阻塞性肺病 (COPD) 研究的潜力。

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SCH 351591 Chemical Structure

SCH 351591 Chemical Structure

CAS No. : 444659-43-2

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SCH 351591 相关抗体

Top Publications Citing Use of Products

查看 Phosphodiesterase (PDE) 亚型特异性产品:

查看所有亚型
PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SCH 351591 is a potent, selective and orally active phosphodiesterase-4 (PDE4) inhibitor with an IC50 of 58 nM. SCH 351591 can inhibit all 4 PDE4 subtypes (A, B, C, and D). SCH 351591 has the potential for the asthma and chronic obstructive pulmonary disease (COPD) research[1].

IC50 & Target[1]

PDE4

58 nM (IC50)

分子量

432.18

Formula

C17H10Cl2F3N3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SCH 351591 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SCH 351591444659-43-2SCH351591SCH-351591Phosphodiesterase (PDE)PDE4 inhibitororally activeasthma chronic obstructive pulmonary disease (COPD)Inhibitorinhibitorinhibit

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